| CAS No.: | 114-86-3 |
|---|---|
| Formula: | C10h15n5 |
| Classification: | High Purity Material |
| Grade: | Pharmaceutcial Grade, AR |
| Specific Usage: | For Tissue Medium Purpose, For Microscopic Purpose, For Electron Microscopy, Pratical Use, Pro Analysis, Super Special Grade, For Electrophoresis Use |
| Content: | 99%Min |
| Samples: |
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| Customization: |
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Suppliers with verified business licenses
Audited Supplier Product Name: Phenformin
CAS: 114-86-3
MF: 10H15N5
MW: 05.26
EINECS:204-057-4
Appearance: white powder
Phenformin, a biguanide with oral hypoglycaemic activity, was introduced in 1957 for the management of diabetes mellitus. By 1970 its use had been associated with incidences of lactic acidosis and by 1976 clinical studies had conclusively demonstrated that the hazards of phenformin treatment outweighed the benefits. Preparations containing phenformin were withdrawn in several countries and their use restricted in others. Elsewhere, however, proprietary preparations containing this drug may remain available. The related biguanide, buformin, has been also associated with lactic acidosis and has been subjected to similar restrictions as phenformin, whereas there is some evidence that metformin is less liable to induce lactic acidosis.
Phenformin is a hydrochloride salt of phenformin from the biguanide drug class that displays anti-diabetic activity. It has been shown to increase AM.PK activity without increasing AMP/ATP activity. A particular study has shown that treating hearts with phenformin hydrochloride and then perfusing with Krebs-Henseleit buffer increased AMP and AM.PK activity and elevated phosphorylated acetyl-CoA carboxylase. Phenformin hydrochloride increases phosphorylation and AM.PK activity in the isolated heart, and this increase has always been correlated with and preceded by increased cytosolic.
Shandong Longilat Biotechnology Co., Ltd was established in 2015. It is a high-tech professional and technological enterprise integrating R & D, production, and sales.
Longilat 's main products are food additives, plant extracts, cosmetic raw materials, feed additives, animal extract, amino acids and vitamins. Most of our products are derived from natural plants. Marketing services are available in many countries around the world.
1.Can I get some samples?
Yes, usually a 10-20g sample.
2.What's your MOQ?
Our MOQ is flexible, usually 1kg-10kg for a trial order is acceptable.
3. Is there a discount?
Of course, welcome to contact us. Price would be different based on different quantities. For bulk quantity, we will have a discount for you.
4. How to deliver the goods?
≤50kg ship by FedEx or DHL etc, ≥50kg ship by Air, ≥100kg can be shipped by Sea. If you have special request on delivery, please contact us.
5. What is the shelf life for the products?
Most products shelf life 24-36 months.
6. What's your delivery time?
Usually, shipment will be made within 7-15 days against confirmed order.
7. How about the validity of the offer?
Usually, our offer is valid for 1 week. However, validity might vary between different products.
Suppliers with verified business licenses
Audited Supplier 
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