| Powder: | Yes |
|---|---|
| Customized: | Non-Customized |
| Certification: | GMP, ISO 9001, USP, BP |
| Suitable for: | Elderly, Adult |
| State: | Solid |
| Purity: | >99% |
| Samples: |
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| Customization: |
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Suppliers with verified business licenses
Audited Supplier | Product name | Apalutamide |
| CAS No. | 111358-88-4 |
| Molecular Formula | C26H21N3O4 |
| Molecular weight | 439.46 |
| Purity | 99% |
| Appearance | White or almost white powder |
| Package | Aluminum Bag;Drums |
| Shelf life | 2 years |
Apalutamide is a white powder, Apalutamide is an androgen receptor antagonist with potential antineoplastic activity. Apalutamide binds to AR in target tissues thereby preventing androgen-induced receptor activation and facilitating the formation of inactive complexes that cannot be translocated to the nucleus. Apalutamide prevents binding to and transcription of AR-responsive genes.
Apalutamide ultimately inhibits the expression of genes that regulate prostate cancer cell proliferation and may lead to an inhibition of cell growth in AR-expressing tumor cells.
| Items | Standards | Results | |
| Appearance | White or off-white powder | Off-white powder | |
| Identification | By HPLC | Complies | |
| Melting Point | 120ºC~130ºC | 126ºC | |
| Loss on Drying | ≤1.00% | 0.21% | |
| Heavy Metals | ≤ 10ppm | Complies | |
| Sulfated Ash | ≤ 0.10% | 0.03% | |
| Chlorine Content | 17.5%~19.5% | 19.3% | |
| Arsenic Content | ≤ 0.1ppm | 0.09ppm | |
| Lead VContent | ≤ 3.0ppm | 0.50ppm | |
| Cadmium Content | ≤ 0.1ppm | 0.10ppm | |
| Mercury Content | ≤ 0.1ppm | 0.10ppm | |
| Microbiological Test | Coliforms:Negative | Negative | |
| Salmonella: Negative | Complies | ||
| Total plate count: ≤1000 CFU/g | Pass | ||
| Yeast&Mold: ≤50 CFU/g | Pass | ||
| Related Substances | Impurity A: ≤0.30% | 0.18% | |
| Other unknown impurity: ≤0.10% | 0.07% | ||
| Total Impurities: ≤0.50% | 0.42% | ||
| Assay | ≥ 98.0% | 99.50% | |
| Reference Standard | USP Standard | ||
| Conclusion | The product complied to USP standard. | ||
| Storage | Preserve in tight,light-resistant containers in a cool place | ||
Apalutamide is used in conjunction with castration, either via bilateral orchiectomy or gonadotropin-releasing hormone analogue (GnRH analogue) therapy, as a method of androgen deprivation therapy in the treatment of NM-CRPC.
Shandong Longilat Biotechnology Co., Ltd was established in 2015. It is a high-tech professional and technological enterprise integrating R & D, production, and sales.
Longilat 's main products are food additives, plant extracts, cosmetic raw materials, feed additives, animal extract, amino acids and vitamins. Most of our products are derived from natural plants. Marketing services are available in many countries around the world.
1.Can I get some samples?
Yes, usually a 10-20g sample.
2.What's your MOQ?
Our MOQ is flexible, usually 1kg-10kg for a trial order is acceptable.
3. Is there a discount?
Of course, welcome to contact us. Price would be different based on different quantities. For bulk quantity, we will have a discount for you.
4. How to deliver the goods?
≤50kg ship by FedEx or DHL etc, ≥50kg ship by Air, ≥100kg can be shipped by Sea. If you have special request on delivery, please contact us.
5. What is the shelf life for the products?
Most products shelf life 24-36 months.
6. What's your delivery time?
Usually, shipment will be made within 7-15 days against confirmed order.
7. How about the validity of the offer?
Usually, our offer is valid for 1 week. However, validity might vary between different products.
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