Customization: | Available |
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Classification: | Organic Analytical Reagents |
Specific Usage: | For Biological Purpose, For Tissue Medium Purpose, For Microbiological, For Microscopic Purpose, For Electron Microscopy, For Lens Blooming |
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Product Name: Ademetionine Disulfate Tosylate
CAS: 97540-22-2
MF: C22H36N6O16S4
Molecular Weight:766.8
Appearance: White powder
Product name: | Ademetionine Disulfate Tosylate | CAS No.: | 97540-22-2 |
MF: | C22H36N6O16S4 | MW: | 766.8 |
Item | Specification |
Assay | >98% |
Appearance | White powder |
Odor | Characteristic |
Taste | Characteristic |
Particle Size | NLT 100% Through 80 mesh |
Loss on Drying | <2.0% |
Heavy metals | ≤10ppm |
Arsenic | ≤3ppm |
Lead | ≤3ppm |
<2.0% | |
Total Plate Count | ≤1000cfu/g |
Total Yeast & Mold | ≤100cfu/g |
E.Coli | Negative |
Salmonella | Negative |
Function
1.S-Adenosyl-L-methionine is a good nutrition for the liver,can prevent alcohol, drugs and the liver-cell injury;
2.S-Adenosyl-L-methionine has remarkable preventive effects on chronic active hepatitis, and other factors caused liver
injury,heart disease, cancer and so on.
3.S-Adenosyl-L-methionine has been found to be as effective as pharmaceutical treatments for arthritis and major
depression as well.
Application
1. S-Adenosyl methionine (SAM, SAMe, SAM-e) is a coenzyme involved in methyl group transfers. It is made from adenosine triphosphate (ATP) and methionine by methionine adenosyltransferase (EC 2.5.1.6). Transmethylation, transsulfuration, and aminopropylation are the metabolic pathways that use SAM. Although these anabolic reactions occur throughout the body, most SAM is produced and consumed in the liver.
2 .The methyl group (CH3) attached to the methionine sulfur atom in SAM is chemically reactive. This allows donation of this group to an acceptor substrate in transmethylation reactions. More than 40 metabolic reactions involve the transfer of a methyl group from SAM to various substrates such as nucleic acids, proteins, and lipids.
3 .In bacteria, SAM is bound by the SAM riboswitch, which regulates genes involved in methionine or cysteine biosynthesis.
4 .Another major role of SAM is in polyamine biosynthesis. Here, SAM is decarboxylated by adenosylmethionine decarboxylase (EC 4.1.1.50) to form S-adenosyl-5'-3-methylpropylamine. This compound then donates its n-propylamine group in the biosynthesis of polyamines such as spermidine and spermine from putrescine.
5 .SAM is required for cellular growth and repair. It is also involved in the biosynthesis of several hormones and neurotransmitters that affect mood, such as dopamine and serotonin. Methyltransferases are also responsible for the addition of methyl groups to the 2' hydroxyls of the first and second nucleotides next to the 5' cap in messenger RNA.
6 .In the United States, SAM is sold as a nutritional supplement under the marketing name SAM-e (also spelled SAME or SAMe). Some research has indicated that taking SAM on a regular basis help fight depression, liver disease, and the pain of osteoarthritis. Multiple clinical trials indicate benefits for depression, some liver conditions and osteoarthritis. All other indications are not yet proven.
Shandong Longilat Biotechnology Co., Ltd was established in 2015. It is a high-tech professional and technological enterprise integrating R & D, production, and sales.
Longilat 's main products are food additives, plant extracts, cosmetic raw materials, feed additives, animal extract, amino acids and vitamins. Most of our products are derived from natural plants. Marketing services are available in many countries around the world.
1.Can I get some samples?
Yes, usually a 10-20g sample.
2.What's your MOQ?
Our MOQ is flexible, usually 1kg-10kg for a trial order is acceptable.
3. Is there a discount?
Of course, welcome to contact us. Price would be different based on different quantities. For bulk quantity, we will have a discount for you.
4. How to deliver the goods?
≤50kg ship by FedEx or DHL etc, ≥50kg ship by Air, ≥100kg can be shipped by Sea. If you have special request on delivery, please contact us.
5. What is the shelf life for the products?
Most products shelf life 24-36 months.
6. What's your delivery time?
Usually, shipment will be made within 7-15 days against confirmed order.
7. How about the validity of the offer?
Usually, our offer is valid for 1 week. However, validity might vary between different products.