Nootropics Raw Powder CAS 148372-04-7 Gts-21

• CAS No.: 156223-05-1
• Formula: C19h22cl2n2o2
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Refined
• Colour: White
• Product Name: Gts-21
• CAS: 156223-05-1
• Grade: Pharmaceutcial Grade
• Storage: Cool Dry Place
• Deliver Time: 5-10 Days
• Test Method: HPLC UV
• Sample: Available
• Shipping Method: Air(UPS, FedEx, TNT, EMS) or Sea
• MW: 381.30
• Mf: C19h22cl2n2o2
• COA: Available
• MOQ: 50 Grams
• Shelf Life: 2 Years
• Transport Package: Bag or Drum
• Specification: 1kg/bag 25kg/drum
• Origin: China
• Production Capacity: 10000kg/Months

Product Description

Product Description

Product Name: Gts-21 Dmbx-Anabaseine
Purity: 99%min by HPLC
CAS No.: 156223-05-1
Appearance: White powder
M.W.: 308.374
M.F.: C19H20N2O2

GTS-21 dihydrochloride is a selective α7 nicotinic acetylcholine receptor agonist, has recently been established as a promising treatment for inflammation. Target: nAChRin vitro: GTS-21 is one of the most potent α7nAChR agonists, has been reported to attenuate pro-inflammatory cytokine production, improve outcomes in sepsis models, pancreatitis, and ischemia-reperfusion injury, and inhibit the production of endotoxin-induced TNF in lung tissue. In addition, recent studies have demonstrated that GTS-21 inhibits the activities of endothelial cells and monocyte macrophages, as well as the secretion of pro-inflammatory cytokines in peripheral blood samples, by regulating the JAK2-STAT3 pathway. [1] in vivo: In septic animals, GTS-21 significantly ameliorated GI motility, lowered systemic and colonic levels of IL-6, decreased colonic permeability, and decreased the number of positive cultures obtained from blood and mesenteric lymph nodes. Splenectomy prevented animals from developing sepsis-induced ileus. Chrna7 mice displayed a more severe septic phenotype, whereas GTS-21 remarkably was also beneficial in these animals.

 

Detailed Photos

 

Function and Application

DMBX-anabaseine (DMBX-A) is a derivative of the natural product anabaseine that acts as a partial agonist at neural nicotinic acetylcholine receptors. It binds to both the α4β2 and α7 subtypes, but activates only the α7 to any significant extent.

Packaging & Shipping

Company Profile

Shandong Longilat Biotechnology Co., Ltd was established in 2015. It is a high-tech professional and technological enterprise integrating R & D, production, and sales. 

Longilat 's main products are food additives, plant extracts, cosmetic raw materials, feed additives, animal extract, amino acids and vitamins. Most of our products are derived from natural plants. Marketing services are available in many countries around the world. 

FAQ

1.Can I get some samples?
Yes, usually a 10-20g sample.

2.What's your MOQ?
Our MOQ is flexible, usually 1kg-10kg for a trial order is acceptable.

3. Is there a discount?
Of course, welcome to contact us. Price would be different based on different quantities. For bulk quantity, we will have a discount for you.

4. How to deliver the goods?
≤50kg ship by FedEx or DHL etc, ≥50kg ship by Air, ≥100kg can be shipped by Sea. If you have special request on delivery, please contact us.

5. What is the shelf life for the products?
Most products shelf life 24-36 months. 

6. What's your delivery time?
Usually, shipment will be made within 7-15 days against confirmed order.

7. How about the validity of the offer? 
Usually, our offer is valid for 1 week. However, validity might vary between different products.